RT Journal Article SR Electronic T1 Severe congenital tricuspid regurgitation in the newborn JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 403 OP 408 VO 52 IS 3 A1 Douglas S. Moodie A1 Richard Sterba A1 Norman B. Ratliff YR 1985 UL http://www.ccjm.org/content/52/3/403.abstract AB A case of congenital tricuspid insufficiency in the newborn secondary to myxomatous degeneration of the tricuspid valve is described. There were myxomatous changes of the pulmonary and aortic valves. The mitral valve was normal. Histologic study showed an increased amount of glycosaminoglycans and a decreased amount of mature collagen of the tricuspid, aortic, and pulmonary valves. The etiology of congenital tricuspid insufficiency of the newborn can be expanded to include failure of the tricuspid valve leaflets to develop normally, a condition that is histologically similar to myxomatous degeneration in the adult.