PT - JOURNAL ARTICLE AU - Bruce W. Lytle AU - Delos M. Cosgrove AU - Judith Borsh AU - Lon A. Castle AU - Floyd D. Loop TI - Mitral valve replacement DP - 1985 Sep 21 TA - Cleveland Clinic Journal of Medicine PG - 369--373 VI - 52 IP - 3 4099 - http://www.ccjm.org/content/52/3/369.short 4100 - http://www.ccjm.org/content/52/3/369.full SO - Cleve Clin J Med1985 Sep 21; 52 AB - Records of the first 100 patients surviving operation for total mitral valve replacement at The Cleveland Clinic Foundation (1962-1964) were reviewed to determine long-term results. After 20 years, 15 patients were still alive, but 13 had sustained a major cardiac event. Complications related to lack of anticoagulant therapy for patients with mechanical prostheses were frequent. No patient-related variable examined appeared to preclude 20-year survival.