TY - JOUR T1 - Mitral valve replacement JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 369 LP - 373 VL - 52 IS - 3 AU - Bruce W. Lytle AU - Delos M. Cosgrove AU - Judith Borsh AU - Lon A. Castle AU - Floyd D. Loop Y1 - 1985/09/21 UR - http://www.ccjm.org/content/52/3/369.abstract N2 - Records of the first 100 patients surviving operation for total mitral valve replacement at The Cleveland Clinic Foundation (1962-1964) were reviewed to determine long-term results. After 20 years, 15 patients were still alive, but 13 had sustained a major cardiac event. Complications related to lack of anticoagulant therapy for patients with mechanical prostheses were frequent. No patient-related variable examined appeared to preclude 20-year survival. ER -