RT Journal Article SR Electronic T1 Affective disorder in bulimic anorexics and their families JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 399 OP 401 VO 52 IS 3 A1 Gregory B. Collins A1 Margaret Kotz A1 Matthew Messina A1 Thomas Ferguson YR 1985 UL http://www.ccjm.org/content/52/3/399.abstract AB A retrospective study of 43 cases of bulimic anorexia and thė patients’ first-degree relatives was done to examine the hypothesis that affective disorder (depression) and bulimic anorexia are related disorders. Twenty-one (48.8%) of the bulimic anorexics were diagnosed as having affective disorder, while 9.3% of the adult female first-degree relatives and 6.8% of the adult male first-degree relatives had affective disorder. This review revealed a high rate of diagnosis of affective disorder among bulimic probands, but not among their family members, whose rates did not differ significantly from those listed for the general population. The reason for the high incidence of affective disorder in bulimic patients is unknown at present, but does suggest that the two disorders are related.