PT  - JOURNAL ARTICLE
AU  - Tsigrelis, Constantine
TI  - Recurrent <em>Clostridioides difficile</em> infection: Recognition, management, prevention
AID  - 10.3949/ccjm.87gr.20001
DP  - 2020 Jun 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 347--359
VI  - 87
IP  - 6
4099  - http://www.ccjm.org/content/87/6/347.short
4100  - http://www.ccjm.org/content/87/6/347.full
SO  - Cleve Clin J Med2020 Jun 01; 87
AB  - Clostridioides difficile infection (CDI) is the most common cause of diarrhea in hospitalized patients and results in substantial morbidity, mortality, and costs. Its clinical management, primarily with antibiotics, is often complicated by recurrent episodes. These recurrent CDI episodes are thought to be caused by antibiotic disruption of colonic microbiota and usually occur within 4 weeks of completing antibiotic therapy. The risk of recurrent CDI increases after the first episode, creating a need for management strategies to diagnose, treat, and prevent these complications.