RT Journal Article
SR Electronic
T1 Recurrent <em>Clostridioides difficile</em> infection: Recognition, management, prevention
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 347
OP 359
DO 10.3949/ccjm.87gr.20001
VO 87
IS 6
A1 Tsigrelis, Constantine
YR 2020
UL http://www.ccjm.org/content/87/6/347.abstract
AB Clostridioides difficile infection (CDI) is the most common cause of diarrhea in hospitalized patients and results in substantial morbidity, mortality, and costs. Its clinical management, primarily with antibiotics, is often complicated by recurrent episodes. These recurrent CDI episodes are thought to be caused by antibiotic disruption of colonic microbiota and usually occur within 4 weeks of completing antibiotic therapy. The risk of recurrent CDI increases after the first episode, creating a need for management strategies to diagnose, treat, and prevent these complications.