RT Journal Article SR Electronic T1 What is the role of supplementation with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic DO 10.3949/ccjm.87a.ccc046 A1 Seth R. Bauer A1 Aanchal Kapoor A1 Mary Rath A1 Suma A. Thomas YR 2020 UL http://www.ccjm.org/content/early/2020/06/02/ccjm.87a.ccc046.abstract AB Several agents intended to supplement dietary intake or endogenous molecules may have a theoretical role in preventing or treating COVID-19. Because of their potential to influence immune response, ascorbic acid (vitamin C), zinc, vitamin D, and N-acetylcysteine have been hypothesized to be useful for prevention or treatment of COVID-19. The authors outline the biologic plausibility, applicable clinical data, and potential role of each of these agents.