TY - JOUR T1 - Clinical presentation and course of COVID-19 JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 384 LP - 388 DO - 10.3949/ccjm.87a.ccc013 VL - 87 IS - 7 AU - Ryan Miller AU - Kristin Englund Y1 - 2020/07/01 UR - http://www.ccjm.org/content/87/7/384.abstract N2 - Information about the clinical presentation and course of COVID-19 is evolving rapidly. On presentation, cough and fever predominate, but extrapulmonary symptoms are also common; in some patients, loss of sense of smell may be an early but favorable sign. The mortality rate varies widely in different reports but should become clearer as more data are collected. Risk factors for severe disease and death include comorbid conditions such as hypertension, cardiovascular disease, diabetes mellitus, and chronic obstructive pulmonary disease. Other implicated factors include older age, obesity, end-stage renal disease, and a higher neutrophil-lymphocyte ratio. ER -