RT Journal Article SR Electronic T1 Clinical presentation and course of COVID-19 JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 384 OP 388 DO 10.3949/ccjm.87a.ccc013 VO 87 IS 7 A1 Ryan Miller A1 Kristin Englund YR 2020 UL http://www.ccjm.org/content/87/7/384.abstract AB Information about the clinical presentation and course of COVID-19 is evolving rapidly. On presentation, cough and fever predominate, but extrapulmonary symptoms are also common; in some patients, loss of sense of smell may be an early but favorable sign. The mortality rate varies widely in different reports but should become clearer as more data are collected. Risk factors for severe disease and death include comorbid conditions such as hypertension, cardiovascular disease, diabetes mellitus, and chronic obstructive pulmonary disease. Other implicated factors include older age, obesity, end-stage renal disease, and a higher neutrophil-lymphocyte ratio.