PT  - JOURNAL ARTICLE
AU  - Spilias, Nikolaos
AU  - Zorach, Benjamin
AU  - Denby, Kara
AU  - Ellis, Stephen
TI  - The role of ISCHEMIA in stable ischemic heart disease
AID  - 10.3949/ccjm.87a.20033
DP  - 2020 Jul 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 401--409
VI  - 87
IP  - 7
4099  - http://www.ccjm.org/content/87/7/401.short
4100  - http://www.ccjm.org/content/87/7/401.full
SO  - Cleve Clin J Med2020 Jul 01; 87
AB  - Although it is well established that adding early revascularization to optimal medical therapy reduces mortality and recurrent myocardial infarction in acute coronary syndrome, there is less convincing evidence to guide intervention in stable ischemic heart disease. This review summarizes the International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial, which investigated whether there is benefit from initial catheterization and possible revascularization in addition to optimal medical therapy in patients with at least moderate ischemia on stress testing.