RT Journal Article
SR Electronic
T1 The role of ISCHEMIA in stable ischemic heart disease
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 401
OP 409
DO 10.3949/ccjm.87a.20033
VO 87
IS 7
A1 Nikolaos Spilias
A1 Benjamin Zorach
A1 Kara Denby
A1 Stephen Ellis
YR 2020
UL http://www.ccjm.org/content/87/7/401.abstract
AB Although it is well established that adding early revascularization to optimal medical therapy reduces mortality and recurrent myocardial infarction in acute coronary syndrome, there is less convincing evidence to guide intervention in stable ischemic heart disease. This review summarizes the International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial, which investigated whether there is benefit from initial catheterization and possible revascularization in addition to optimal medical therapy in patients with at least moderate ischemia on stress testing.