PT - JOURNAL ARTICLE AU - Mucha, Simon R. AU - Dugar, Siddharth AU - McCrae, Keith AU - Joseph, Douglas AU - Bartholomew, John AU - Sacha, Gretchen L. AU - Militello, Michael TI - Coagulopathy in COVID-19: Manifestations and management AID - 10.3949/ccjm.87a.ccc024 DP - 2020 Aug 01 TA - Cleveland Clinic Journal of Medicine PG - 461--468 VI - 87 IP - 8 4099 - http://www.ccjm.org/content/87/8/461.short 4100 - http://www.ccjm.org/content/87/8/461.full SO - Cleve Clin J Med2020 Aug 01; 87 AB - Severe COVID-19 illness is associated with intense inflammation, leading to high rates of thrombotic complications that increase morbidity and mortality. Markedly elevated levels of D-dimer with normal fibrinogen levels are the hallmark laboratory findings of severe COVID-19– associated coagulopathy. Prophylaxis against venous thromboembolism is paramount for all hospitalized patients, with more aggressive prophylaxis and screening recommended for patients with D-dimer levels above 3.0 μg/mL. Point-of-care ultrasonography is the imaging method of choice for patients at high risk, as it entails minimal risk of exposing providers to the virus.