RT Journal Article
SR Electronic
T1 COVID-19 and the kidney
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 619
OP 631
DO 10.3949/ccjm.87a.20072
VO 87
IS 10
A1 Mohamed Hassanein
A1 Yeshwanter Radhakrishnan
A1 John Sedor
A1 Tushar Vachharajani
A1 Vidula T. Vachharajani
A1 Joshua Augustine
A1 Sevag Demirjian
A1 George Thomas
YR 2020
UL http://www.ccjm.org/content/87/10/619.abstract
AB COVID-19 is primarily considered a respiratory illness, but the kidney may be one of the targets of SARS-CoV-2 infection, since the virus enters cells through the angiotensin-converting enzyme 2 receptor, which is found in abundance in the kidney. Information on kidney involvement in COVID-19 is limited but is evolving rapidly. This article discusses the pathogenesis of acute kidney injury (AKI) in COVID-19, its optimal management, and the impact of COVID-19 on patients with chronic kidney disease, patients with end-stage kidney disease on dialysis, and kidney transplant recipients.