TY - JOUR T1 - Update to coagulopathy in COVID-19: Manifestations and management JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med DO - 10.3949/ccjm.87a.ccc024-up AU - Simon R. Mucha AU - Siddharth Dugar AU - Keith McCrae AU - Douglas Joseph AU - John Bartholomew AU - Gretchen L. Sacha AU - Michael Militello Y1 - 2020/12/15 UR - http://www.ccjm.org/content/early/2020/12/14/ccjm.87a.ccc024-up.abstract N2 - Severe COVID-19 illness is associated with intense inflammation, leading to high rates of thrombotic complications that increase morbidity and mortality. Markedly elevated levels of D-dimer with normal fibrinogen levels are the hallmark laboratory findings of severe COVID-19–associated coagulopathy. Prophylaxis against venous thromboembolism is paramount for all hospitalized patients with COVID-19, with more aggressive prophylaxis and screening recommended for critically ill patients with D-dimer levels above 3.0 μg/mL. Point-of-care ultrasonography is the imaging method of choice for patients at high risk, as it entails minimal risk of exposing providers to the virus. ER -