RT Journal Article SR Electronic T1 Anti-Xa assays: What is their role today in antithrombotic therapy? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 417 OP 425 DO 10.3949/ccjm.86a.18029 VO 86 IS 6 A1 Erika Hutt Centeno A1 Michael Militello A1 Marcelo P. Gomes YR 2019 UL http://www.ccjm.org/content/86/6/417.abstract AB Although some suggest anti-Xa assays should be the preferred method for monitoring intravenous unfractionated heparin therapy, which method is best is unknown owing to the lack of large randomized controlled trials correlating different assays with clinical outcomes. This article provides an overview of heparin monitoring and the pros, cons, and clinical applications of anti-Xa assays.