@article {Calabrese, author = {Leonard H. Calabrese and Tiphaine Lenfant and Cassandra Calabrese}, title = {Cytokine storm release syndrome and the prospects for immunotherapy with COVID-19, part 4: The role of JAK inhibition}, year = {2020}, doi = {10.3949/ccjm.87a.ccc060}, publisher = {Cleveland Clinic Journal of Medicine}, abstract = {This review focuses on an alternative strategy utilizing small molecules to inhibit a key signal-transduction pathway, the Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathway. The JAK-STAT pathway mediates biologic activity for a large number of inflammatory cytokines and mediators.}, issn = {0891-1150}, URL = {https://www.ccjm.org/content/early/2021/02/11/ccjm.87a.ccc060}, eprint = {https://www.ccjm.org/content/early/2021/02/11/ccjm.87a.ccc060.full.pdf}, journal = {Cleveland Clinic Journal of Medicine} }