PT  - JOURNAL ARTICLE
AU  - Gary W. Procop
AU  - Kamran Kadkhoda
AU  - Daniel D. Rhoads
AU  - Steven G. Gordon
AU  - Anita J. Reddy
TI  - Home testing for COVID-19: Benefits and limitations
AID  - 10.3949/ccjm.88a.ccc071
DP  - 2021 Feb 12
TA  - Cleveland Clinic Journal of Medicine
4099  - http://www.ccjm.org/content/early/2021/02/24/ccjm.88a.ccc071.short
4100  - http://www.ccjm.org/content/early/2021/02/24/ccjm.88a.ccc071.full
AB  - The home test kits for detecting SARS-CoV-2 infection with Food and Drug Administration emergency use authorization primarily use either isothermal nucleic acid amplification or antigen detection, and each test has advantages and limitations in terms of sensitivity and specificity, cost, results reporting, and results turnaround time. In clinical studies, these tests provide accurate positive results in symptomatic individuals, although negative results are less accurate. There are also accuracy concerns for positive results in asymptomatic individuals. These factors have implications for their clinical interpretation and use.