RT Journal Article SR Electronic T1 Home testing for COVID-19: Benefits and limitations JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic DO 10.3949/ccjm.88a.ccc071 A1 Procop, Gary W. A1 Kadkhoda, Kamran A1 Rhoads, Daniel D. A1 Gordon, Steven G. A1 Reddy, Anita J. YR 2021 UL http://www.ccjm.org/content/early/2021/02/24/ccjm.88a.ccc071.abstract AB The home test kits for detecting SARS-CoV-2 infection with Food and Drug Administration emergency use authorization primarily use either isothermal nucleic acid amplification or antigen detection, and each test has advantages and limitations in terms of sensitivity and specificity, cost, results reporting, and results turnaround time. In clinical studies, these tests provide accurate positive results in symptomatic individuals, although negative results are less accurate. There are also accuracy concerns for positive results in asymptomatic individuals. These factors have implications for their clinical interpretation and use.