PT - JOURNAL ARTICLE AU - Chao-Ping Wu AU - Fatima Adhi AU - Daniel Culver TI - Vaccination for COVID-19: Is it important and what should you know about it? AID - 10.3949/ccjm.88a.ccc076 DP - 2021 Mar 09 TA - Cleveland Clinic Journal of Medicine 4099 - http://www.ccjm.org/content/early/2021/03/10/ccjm.88a.ccc076.short 4100 - http://www.ccjm.org/content/early/2021/03/10/ccjm.88a.ccc076.full AB - An effective vaccine is considered the best method to achieve herd immunity. As of February 2021, 12 vaccines were in late-stage clinical trials worldwide, with many more in development. Of those, 8 have received emergency use authorization from at least one country’s governing body. These vaccines use various platforms to deliver the vaccines, each with pros and cons. Published data show these vaccines are effective in preventing the severe symptoms associated with COVID-19 in adults with few side effects, but challenges remain with storage and delivery and treating virus variants.