PT  - JOURNAL ARTICLE
AU  - Modesto-Lowe, Vania
AU  - Harabasz, Agata K.
AU  - Walker, Sophia A.
TI  - Quetiapine for primary insomnia: Consider the risks
AID  - 10.3949/ccjm.88a.20031
DP  - 2021 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 286--294
VI  - 88
IP  - 5
4099  - http://www.ccjm.org/content/88/5/286.short
4100  - http://www.ccjm.org/content/88/5/286.full
SO  - Cleve Clin J Med2021 May 01; 88
AB  - The second-generation antipsychotic drug quetiapine (Seroquel) is increasingly being used off-label for treating insomnia in the general population, possibly to avoid standard medications with known addictive qualities and adverse side effects. However, evidence to support using it in this way is scant, and quetiapine is associated with weight gain and other metabolic effects. It must be used cautiously and with appropriate monitoring for adverse effects and abuse.