PT - JOURNAL ARTICLE AU - McCrae, Keith R. TI - Thrombotic thrombocytopenia due to SARS-CoV-2 vaccination AID - 10.3949/ccjm.88a.ccc078 DP - 2021 May 06 TA - Cleveland Clinic Journal of Medicine 4099 - http://www.ccjm.org/content/early/2021/05/06/ccjm.88a.ccc078.short 4100 - http://www.ccjm.org/content/early/2021/05/06/ccjm.88a.ccc078.full AB - Vaccine-induced thrombotic thrombocytopenia (VITT) has been reported after vaccination with the AztraZeneca ChAdOx1 nCoV-19 and the Johnson and Johnson Ad26. COV2.S vaccines. This manuscript provides a brief overview of reported cases, clinical and laboratory features, and current understanding of the pathogenesis of VITT. The author also poses unananswered questions and identifies directions for future study.