PT - JOURNAL ARTICLE AU - Siddharth Dugar AU - Chirag Choudhary AU - Abhijit Duggal TI - Sepsis and septic shock: Guideline-based management AID - 10.3949/ccjm.87a.18143 DP - 2020 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 53--64 VI - 87 IP - 1 4099 - http://www.ccjm.org/content/87/1/53.short 4100 - http://www.ccjm.org/content/87/1/53.full SO - Cleve Clin J Med2020 Jan 01; 87 AB - Sepsis is a life-threatening organ dysfunction that results from the body’s response to infection. It requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and control of the source of infection. With the trend in management moving away from protocolized care in favor of appropriate usual care, an understanding of sepsis physiology and best practice guidelines is critical.