RT Journal Article SR Electronic T1 Sepsis and septic shock: Guideline-based management JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 53 OP 64 DO 10.3949/ccjm.87a.18143 VO 87 IS 1 A1 Siddharth Dugar A1 Chirag Choudhary A1 Abhijit Duggal YR 2020 UL http://www.ccjm.org/content/87/1/53.abstract AB Sepsis is a life-threatening organ dysfunction that results from the body’s response to infection. It requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and control of the source of infection. With the trend in management moving away from protocolized care in favor of appropriate usual care, an understanding of sepsis physiology and best practice guidelines is critical.