RT Journal Article SR Electronic T1 Antiobesity drug therapy: An individualized and comprehensive approach JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 440 OP 448 DO 10.3949/ccjm.88a.20080 VO 88 IS 8 A1 Yael Mauer A1 Marcie Parker A1 Sangeeta R. Kashyap YR 2021 UL http://www.ccjm.org/content/88/8/440.abstract AB Obesity affects 42% of US adults and has a devastating impact on health. Although many patients initially lose weight with diet and exercise, long-term weight loss is difficult to achieve. Pharmacotherapy, as part of a comprehensive plan, can help patients lose weight and avoid regaining it. Choosing an antiobesity drug regimen should be an individualized, shared decision-making process that accounts for patient preferences, comorbidities, and out-of-pocket costs. We review antiobesity drugs and propose an individualized and comprehensive approach to obesity management.