PT - JOURNAL ARTICLE AU - Asad Khan AU - Erik H. Van Iterson AU - Luke J. Laffin TI - The obesity paradox in heart failure: What is the role of cardiorespiratory fitness? AID - 10.3949/ccjm.88a.20098 DP - 2021 Aug 01 TA - Cleveland Clinic Journal of Medicine PG - 449--458 VI - 88 IP - 8 4099 - http://www.ccjm.org/content/88/8/449.short 4100 - http://www.ccjm.org/content/88/8/449.full SO - Cleve Clin J Med2021 Aug 01; 88 AB - The obesity paradox describes a survival benefit for higher body mass index in patients with heart failure. But other factors like cardiorespiratory fitness may play a role in heart failure development, severity, and survival. Although more research is needed to better understand the relationships between body mass index and fitness in patients with heart failure, evidence indicates that recommending weight loss and an exercise program is appropriate for most patients.