RT Journal Article SR Electronic T1 Sickle cell disease: A primary care update JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 19 OP 27 DO 10.3949/ccjm.87a.18051 VO 87 IS 1 A1 Grace Onimoe A1 Seth Rotz YR 2020 UL http://www.ccjm.org/content/87/1/19.abstract AB Sickle cell disease (SCD) is the most common hemoglobinopathy in the United States and causes significant disease-related morbidity including multiorgan damage, chronic anemia, and debilitating pain crises. Primary care physicians play a key role in the medical home model of care for adults with SCD. This review focuses on current recommendations for health maintenance and provides a brief summary of disease complications and current updates.