RT Journal Article SR Electronic T1 COVID-19 in older adults JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic DO 10.3949/ccjm.88a.ccc080 A1 Saket Saxena A1 Ardeshir Z. Hashmi YR 2021 UL http://www.ccjm.org/content/early/2021/09/14/ccjm.88a.ccc080.abstract AB The impact of COVID-19 varies by age group, and it has become clear that individuals over 65 years are disproportionately impacted by COVID-19 both in terms of severity of illness and mortality. Atypical presentations in older adults may result from pathophysiologic changes during aging and immune dysregulation because of the cumulative impact of chronic comorbidities. Herein we review the different clinical presentations of illness for older adults, the unique challenges faced by this population, and strategies for treatment.