RT Journal Article
SR Electronic
T1 Risk-based guidelines: Redefining management of abnormal cervical cancer screening results
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 556
OP 560
DO 10.3949/ccjm.88a.20193
VO 88
IS 10
A1 Amy Wiser
A1 Jeffrey D. Quinlan
A1 Pelin Batur
YR 2021
UL http://www.ccjm.org/content/88/10/556.abstract
AB In making the 2019 guidelines for risk-based management of patients with abnormal cervical cancer screening tests and cancer precursors, the guidelines committee shifted from results-based to risk-based management recommendations, based on the patient’s immediate and 5-year risks of grade 3 or higher cervical intraepithelial neoplasia (CIN 3+). The risk is determined by current and prior screening results (human papillomavirus infection, cytology testing) and the clinical history including age. An immediate 4% or higher risk of CIN 3+ was established as the dividing line between higher and lower risks, and the corresponding management recommendations. This article reviews the changes and their evidence base and discusses clinical implications of the revised guidelines.