PT - JOURNAL ARTICLE AU - Susan Vehar AU - Marina Boushra AU - Prince Ntiamoah AU - Michelle Biehl TI - Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the 'long-haulers' AID - 10.3949/ccjm.88a.21010-up DP - 2021 Oct 08 TA - Cleveland Clinic Journal of Medicine 4099 - http://www.ccjm.org/content/early/2021/09/30/ccjm.88a.21010-up.short 4100 - http://www.ccjm.org/content/early/2021/09/30/ccjm.88a.21010-up.full AB - An estimated 10% of COVID-19 survivors continue to experience symptoms several weeks to months after the appearance of initial symptoms, a condition termed post-acute sequelae of SARS-CoV-2 infection (PASC). These patients, also called “long-haulers,” most commonly report protracted symptoms of fatigue, cough, dyspnea, chest tightness, difficulty concentrating, arthralgia, olfactory dysfunction, and headache. While age, comorbid medical conditions, and COVID-19 severity are suspected risk factors for PASC, young and previously healthy individuals with mild COVID-19 are also at risk. Recognition of symptoms, evaluation, supportive treatment, and attention to medical comorbidities are the cornerstones of medical management.