PT - JOURNAL ARTICLE AU - Sherwin DeSouza AU - Dana Angelini TI - Updated guidelines for immune thrombocytopenic purpura: Expanded management options AID - 10.3949/ccjm.88a.20201 DP - 2021 Dec 01 TA - Cleveland Clinic Journal of Medicine PG - 664--668 VI - 88 IP - 12 4099 - http://www.ccjm.org/content/88/12/664.short 4100 - http://www.ccjm.org/content/88/12/664.full SO - Cleve Clin J Med2021 Dec 01; 88 AB - The current American Society of Hematology (ASH) guidelines for the management of patients with immune thrombocytopenic purpura (ITP) are an update to the 2011 guidelines. The updates focus on treating patients with ITP without bleeding in both outpatient and inpatient settings, including those with newly diagnosed, persistent, and chronic ITP refractory to first-line therapy. Recommendations for therapy include corticosteroids, intravenous immunoglobulins, anti-D immunoglobulin, rituximab, splenectomy, and thrombopoietin-receptor agonists, as well as observation.