PT  - JOURNAL ARTICLE
AU  - Amgad N. Makaryus
AU  - Samy I. McFarlane
TI  - Diabetes insipidus: Diagnosis and treatment of a complex disease
DP  - 2006 Jan 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 65--71
VI  - 73
IP  - 1
4099  - http://www.ccjm.org/content/73/1/65.short
4100  - http://www.ccjm.org/content/73/1/65.full
SO  - Cleve Clin J Med2006 Jan 01; 73
AB  - Diabetes insipidus, characterized by excretion of copious volumes of dilute urine, can be life-threatening if not properly diagnosed and managed. It can be caused by two fundamentally different defects: inadequate or impaired secretion of antidiuretic hormone (ADH) from the posterior pituitary gland (neurogenic or central diabetes insipidus) or impaired or insufficient renal response to ADH (nephrogenic diabetes insipidus). The distinction is essential for effective treatment.