RT Journal Article
SR Electronic
T1 Diabetes insipidus: Diagnosis and treatment of a complex disease
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 65
OP 71
VO 73
IS 1
A1 Amgad N. Makaryus
A1 Samy I. McFarlane
YR 2006
UL http://www.ccjm.org/content/73/1/65.abstract
AB Diabetes insipidus, characterized by excretion of copious volumes of dilute urine, can be life-threatening if not properly diagnosed and managed. It can be caused by two fundamentally different defects: inadequate or impaired secretion of antidiuretic hormone (ADH) from the posterior pituitary gland (neurogenic or central diabetes insipidus) or impaired or insufficient renal response to ADH (nephrogenic diabetes insipidus). The distinction is essential for effective treatment.