PT - JOURNAL ARTICLE AU - Christopher Sibley AU - Neil J. Stone TI - Familial hypercholesterolemia: A challenge of diagnosis and therapy DP - 2006 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 57--64 VI - 73 IP - 1 4099 - http://www.ccjm.org/content/73/1/57.short 4100 - http://www.ccjm.org/content/73/1/57.full SO - Cleve Clin J Med2006 Jan 01; 73 AB - People with familial hypercholesterolemia (FH) have dramatically high levels of low-density lipoprotein cholesterol (LDL-C), which can lead to accelerated atherosclerosis and, if untreated, early cardiovascular death. Although the heterozygous form of FH is often unrecognized, detecting it early can enable risk reduction before premature coronary heart disease occurs.