PT - JOURNAL ARTICLE AU - Abel Joseph AU - Siva Raja AU - Suneel Kamath AU - Sunguk Jang AU - Daniela Allende AU - Mike McNamara AU - Gregory Videtic AU - Sudish Murthy AU - Amit Bhatt TI - Esophageal adenocarcinoma: A dire need for early detection and treatment AID - 10.3949/ccjm.89a.21053 DP - 2022 May 01 TA - Cleveland Clinic Journal of Medicine PG - 269--279 VI - 89 IP - 5 4099 - http://www.ccjm.org/content/89/5/269.short 4100 - http://www.ccjm.org/content/89/5/269.full SO - Cleve Clin J Med2022 May 01; 89 AB - Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Esophageal adenocarcinoma is the most common subtype of esophageal cancer in the United States, and its incidence has risen dramatically in the last few decades. Modern endoscopic and surgical techniques have significantly improved morbidity and mortality rates of patients undergoing treatment for esophageal cancer. However, most cases are diagnosed at a late stage when the prognosis is poor, emphasizing the need for an effective screening strategy. This clinical overview focuses on screening, multidisciplinary evaluation, and treatment of early esophageal adenocarcinoma.