RT Journal Article SR Electronic T1 Esophageal adenocarcinoma: A dire need for early detection and treatment JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 269 OP 279 DO 10.3949/ccjm.89a.21053 VO 89 IS 5 A1 Abel Joseph A1 Siva Raja A1 Suneel Kamath A1 Sunguk Jang A1 Daniela Allende A1 Mike McNamara A1 Gregory Videtic A1 Sudish Murthy A1 Amit Bhatt YR 2022 UL http://www.ccjm.org/content/89/5/269.abstract AB Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Esophageal adenocarcinoma is the most common subtype of esophageal cancer in the United States, and its incidence has risen dramatically in the last few decades. Modern endoscopic and surgical techniques have significantly improved morbidity and mortality rates of patients undergoing treatment for esophageal cancer. However, most cases are diagnosed at a late stage when the prognosis is poor, emphasizing the need for an effective screening strategy. This clinical overview focuses on screening, multidisciplinary evaluation, and treatment of early esophageal adenocarcinoma.