RT Journal Article SR Electronic T1 Anticoagulation management of post-cardiac surgery new-onset atrial fibrillation JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 329 OP 335 DO 10.3949/ccjm.89a.21003 VO 89 IS 6 A1 Ghaith Alhatemi A1 Mohamed Zghouzi A1 Yasar Sattar A1 Bachar Ahmad A1 Waqas Ullah A1 M. Chadi Alraies YR 2022 UL http://www.ccjm.org/content/89/6/329.abstract AB New-onset post-cardiac surgery atrial fibrillation (PCSAF) is a frequent complication with estimated incidence of 17% to 64%, depending on type of surgery. It is associated with higher mortality, morbidity, and predisposition to stroke and systemic embolism postoperatively. Standard care involves rate or rhythm control, in addition to antithrombotic therapy in those with history of stroke, transient ischemic attack, or high risk of systemic thromboembolism. However, risk of bleeding is not negligible, and treating physicians should weigh the risks and benefits before committing to postoperative anticoagulation therapy. More investigations are warranted to explore antithrombotic therapy benefit, particularly postoperative anticoagulation, considering the potentially self-limited nature of the arrhythmia and high risk of postoperative bleeding.