PT - JOURNAL ARTICLE AU - Ardakani, Amir Hossain Gahanbani AU - Faimali, Martina AU - Nystrom, Lukas AU - Mesko, Nathan AU - Mughal, Muntzer AU - Ware, Howard AU - Gikas, Panagiotis TI - Metastatic bone disease: Early referral for multidisciplinary care AID - 10.3949/ccjm.89a.21062 DP - 2022 Jul 01 TA - Cleveland Clinic Journal of Medicine PG - 393--399 VI - 89 IP - 7 4099 - http://www.ccjm.org/content/89/7/393.short 4100 - http://www.ccjm.org/content/89/7/393.full SO - Cleve Clin J Med2022 Jul 01; 89 AB - It is estimated that more than half of all cancers develop bony metastases, exacting a substantial cost in terms of patient quality of life and healthcare expenses. Prompt diagnosis and management have been shown to reduce morbidity and costs. When a patient with a history of cancer presents with musculoskeletal pain, heightened awareness of the risk of bone metastasis should prompt immediate referral to an orthopedic specialist. A multidisciplinary approach is needed to identify an appropriate treatment plan for the patient based on the prognosis, fracture status, and extent of skeletal disease.