RT Journal Article SR Electronic T1 Metastatic bone disease: Early referral for multidisciplinary care JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 393 OP 399 DO 10.3949/ccjm.89a.21062 VO 89 IS 7 A1 Amir Hossain Gahanbani Ardakani A1 Martina Faimali A1 Lukas Nystrom A1 Nathan Mesko A1 Muntzer Mughal A1 Howard Ware A1 Panagiotis Gikas YR 2022 UL http://www.ccjm.org/content/89/7/393.abstract AB It is estimated that more than half of all cancers develop bony metastases, exacting a substantial cost in terms of patient quality of life and healthcare expenses. Prompt diagnosis and management have been shown to reduce morbidity and costs. When a patient with a history of cancer presents with musculoskeletal pain, heightened awareness of the risk of bone metastasis should prompt immediate referral to an orthopedic specialist. A multidisciplinary approach is needed to identify an appropriate treatment plan for the patient based on the prognosis, fracture status, and extent of skeletal disease.