PT  - JOURNAL ARTICLE
AU  - Rebecca H. Sunenshine
AU  - L. Clifford McDonald
TI  - <em>Clostridium difficile</em>-associated disease: New challenges from an established pathogen
DP  - 2006 Feb 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 187--197
VI  - 73
IP  - 2
4099  - http://www.ccjm.org/content/73/2/187.short
4100  - http://www.ccjm.org/content/73/2/187.full
SO  - Cleve Clin J Med2006 Feb 01; 73
AB  - Clostridium difficile-associated disease (CDAD) can range from uncomplicated diarrhea to sepsis and even death. CDAD rates and severity are increasing, possibly due to a new strain. Transmission of C difficile occurs primarily in health care facilities via the fecal-oral route following transient contamination of the hands of health care workers and patients; contamination of the patient care environment also plays an important role.