%0 Journal Article %A Essa H. Hariri %A Mazen M. Al Hammoud %A Steven E. Nissen %A Donald F. Hammer %T Primary and secondary prevention of atherosclerotic cardiovascular disease: A case-based approach %D 2022 %R 10.3949/ccjm.89a.21103 %J Cleveland Clinic Journal of Medicine %P 513-522 %V 89 %N 9 %X Estimating the risk of atherosclerotic cardiovascular disease (ASCVD) is a daily challenge for clinicians and is crucial to tailoring preventive medical care and guiding shared decision-making. New imaging modalities and novel biomarkers allow for more accurate assessment of patient risk and minimize the risk of over- or undertreating patients. Major cardiovascular medicine societies have incorporated new diagnostic modalities in their guidelines to aid clinical decision-making for primary and secondary prevention of ASCVD. This review presents commonly encountered cases relevant to estimating and reducing ASCVD risk based on available guidelines and expert opinion. %U https://www.ccjm.org/content/ccjom/89/9/513.full.pdf