RT Journal Article SR Electronic T1 Diagnostic stewardship for urinary tract infection: A snapshot of the expert guidance JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 581 OP 587 DO 10.3949/ccjm.89a.22008 VO 89 IS 10 A1 Werneburg, Glenn T. A1 Rhoads, Daniel D. YR 2022 UL http://www.ccjm.org/content/89/10/581.abstract AB The urine culture, the cornerstone for laboratory diagnosis of urinary tract infection (UTI), is associated with a high frequency of false-positive and false-negative results, and its diagnostic threshold is debated. Urine culture takes days to result, and antibiotics are often initiated while awaiting final culture readings. Further, asymptomatic bacteriuria—the presence of bacteria in urine in the absence of UTI symptoms—generally does not warrant treatment. The authors review current expert guidance on the use of urine culture, including approaches to ordering, processing, and reporting of urine cultures, with the goal of reducing unnecessary antibiotic use and misdiagnosis of UTI.