PT - JOURNAL ARTICLE AU - Leonard Calabrese TI - The yin and yang of tumor necrosis factor inhibitors DP - 2006 Mar 01 TA - Cleveland Clinic Journal of Medicine PG - 251--256 VI - 73 IP - 3 4099 - http://www.ccjm.org/content/73/3/251.short 4100 - http://www.ccjm.org/content/73/3/251.full SO - Cleve Clin J Med2006 Mar 01; 73 AB - Tumor necrosis factor (TNF) inhibitors have proven highly effective against a number of autoimmune diseases but have been disappointing in treating others. An increase in the risk of Mycobacterium tuberculosis and other opportunistic infections has been noted in patients treated with these agents. If we use these drugs, we need to weigh their beneficial and adverse effects.