PT - JOURNAL ARTICLE AU - Yahr, Jordana AU - Thomas, George AU - Calle, Juan AU - Taliercio, Jonathan J. TI - Resistant hypertension: A stepwise approach AID - 10.3949/ccjm.90a.22046 DP - 2023 Feb 01 TA - Cleveland Clinic Journal of Medicine PG - 115--125 VI - 90 IP - 2 4099 - http://www.ccjm.org/content/90/2/115.short 4100 - http://www.ccjm.org/content/90/2/115.full SO - Cleve Clin J Med2023 Feb 01; 90 AB - Resistant hypertension can be challenging to manage, but a stepwise approach to diagnosis, evaluation, and treatment can lead to better blood pressure control. In this article, we review the definition and prevalence of resistant hypertension and its diagnostic workup and management, including lifestyle modifications, drugs, and experimental interventional therapies.