PT  - JOURNAL ARTICLE
AU  - Paolo Sossai
AU  - Domenico Staiti
AU  - Massimiliano Cannas
AU  - Piero Grima
TI  - Smallpox and monkeypox: Looking back and looking ahead
AID  - 10.3949/ccjm.90a.22067
DP  - 2023 Mar 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 141--144
VI  - 90
IP  - 3
4099  - http://www.ccjm.org/content/90/3/141.short
4100  - http://www.ccjm.org/content/90/3/141.full
SO  - Cleve Clin J Med2023 Mar 01; 90
AB  - The monkeypox (mpox) epidemic was declared a global health emergency in July 2022. The mpox virus belongs to the same virus family as the smallpox, or variola virus, but the infection is a less lethal threat than smallpox. Nevertheless, its relationship to smallpox is a worldwide concern, as is the discontinuation of universal smallpox vaccinations since the 1980s. Newer therapies and vaccines are available for both infections, including 2 antiviral drugs that can be used under certain conditions. Two vaccines have been developed for mpox prevention, but clarity is needed on when and how to use them. Preventive public health measures and prioritization of resources for managing infectious disease are concerns.