RT Journal Article SR Electronic T1 Diagnosis and management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 209 OP 213 DO 10.3949/ccjm.90a.22028 VO 90 IS 4 A1 Khan, Sarah A1 Linganna, Maureen YR 2023 UL http://www.ccjm.org/content/90/4/209.abstract AB Ascites is the most common decompensation-associated complication of cirrhosis leading to reduced survival. Following significant development of antimicrobial resistance and studies comparing therapeutic options, the American Association for the Study of Liver Diseases released a new guidance providing an in-depth review of those studies and updated guidelines based on expert opinions and emerging data. We review salient 2021 guidance recommendations to provide brief pearls for diagnosis and management of ascites and relevant conditions associated with decompensated cirrhosis, such as hyponatremia, hepatic hydrothorax, spontaneous bacterial peritonitis, and hepatorenal syndrome, and use of transjugular intrahepatic shunt.