TY - JOUR T1 - Central sensitization, chronic pain, and other symptoms: Better understanding, better management JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 245 LP - 254 DO - 10.3949/ccjm.90a.22019 VL - 90 IS - 4 AU - Mary M. Volcheck AU - Stephanie M. Graham AU - Kevin C. Fleming AU - Arya B. Mohabbat AU - Connie A. Luedtke Y1 - 2023/04/01 UR - http://www.ccjm.org/content/90/4/245.abstract N2 - Central sensitization, a pathophysiologic process in which the central nervous system undergoes changes that alter its processing of pain and other sensory stimuli, may be the mechanism underlying various conditions in which patients have unexplained pain and fatigue. Patients frequently misunderstand the cause of their symptoms and pursue unnecessary evaluations and treatments. Clinicians have a pivotal role in decreasing this misunderstanding by providing patient education, which can affect perception, management, functional status, and quality of life. ER -