RT Journal Article SR Electronic T1 Heart failure with reduced ejection fraction: What’s new in the 2022 guideline? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 215 OP 220 DO 10.3949/ccjm.90a.22101 VO 90 IS 4 A1 Kittleson, Michelle M. YR 2023 UL http://www.ccjm.org/content/90/4/215.abstract AB The 2022 guideline from the American College of Cardiology, American Heart Association, and Heart Failure Society of America provides practical recommendations for preventing, diagnosing, and managing patients with heart failure. This article summarizes the most important of these recommendations, specifically for managing patients with heart failure with reduced ejection fraction (HFrEF), and how they should change daily practice.