RT Journal Article SR Electronic T1 Reproductive issues and multiple sclerosis: 20 questions JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 235 OP 243 DO 10.3949/ccjm.90a.22066 VO 90 IS 4 A1 Alise K. Carlson A1 Daniel Ontaneda A1 Mary R. Rensel A1 Jeffrey A. Cohen A1 Amy Kunchok YR 2023 UL http://www.ccjm.org/content/90/4/235.abstract AB Multiple sclerosis (MS) is commonly diagnosed in young adults during their reproductive years. Consequently, concerns about family planning and MS management related to pregnancy and breastfeeding are often encountered in clinical practice. Pregnancy itself is not harmful for women with MS. However, disease-modifying therapies (DMTs) have implications for reproductive planning, including stopping treatment while trying to conceive and during pregnancy, as well as managing fetal risks. People with MS and their care team must engage in collaborative decision-making before, during, and after pregnancy. Based on the results of a consensus-building initiative, answers are provided to 20 frequently asked questions regarding the management of MS during pregnancy planning, pregnancy, and the postpartum period.