PT  - JOURNAL ARTICLE
AU  - Jonathan J. Taliercio
AU  - Ali Mehdi
TI  - IgA nephropathy
AID  - 10.3949/ccjm.90.e-s1.02
DP  - 2023 Jun 01
TA  - Cleveland Clinic Journal of Medicine
PG  - e5--e8
VI  - 90
IP  - 6 suppl 1
4099  - http://www.ccjm.org/content/90/6_suppl_1/e5.short
4100  - http://www.ccjm.org/content/90/6_suppl_1/e5.full
SO  - Cleve Clin J Med2023 Jun 01; 90
AB  - Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis in the world. The etiology is unknown but a dysregulated T-cell immune response to viral, bacterial, and food antigens activating mucosal plasma cells to produce polymeric IgA has been proposed. No serological test exists to diagnosis IgAN. A definitive diagnosis requires kidney biopsy which is not always necessary. Kidney failure occurs in 20% to 40% of patients within 10 to 20 years.