TY - JOUR T1 - IgA nephropathy JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - e5 LP - e8 DO - 10.3949/ccjm.90.e-s1.02 VL - 90 IS - 6 suppl 1 AU - Jonathan J. Taliercio AU - Ali Mehdi Y1 - 2023/06/01 UR - http://www.ccjm.org/content/90/6_suppl_1/e5.abstract N2 - Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis in the world. The etiology is unknown but a dysregulated T-cell immune response to viral, bacterial, and food antigens activating mucosal plasma cells to produce polymeric IgA has been proposed. No serological test exists to diagnosis IgAN. A definitive diagnosis requires kidney biopsy which is not always necessary. Kidney failure occurs in 20% to 40% of patients within 10 to 20 years. ER -